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Opana ER is a prescription opioid medication used to manage severe pain. It contains oxymorphone, a potent pain reliever that can be habit-forming and may lead to abuse. the most reliable and secure websites to buy Opana ER by credit card is the online pharmacy, Your Meds. Your Meds is a licensed online pharmacy that specializes in providing prescription medication at an affordable price. They have been in the business for over a decade and have built a reputation for their high-quality products and excellent customer service.